AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |
Back to Blog
Does cleroderma affect the lungs2/10/2024 Pulmonary FDG uptakes were positively correlated with the ILD severity (fibrosis extent, %FVC, and %D LCO). Pulmonary FDG uptakes were higher in SSc patients than in controls ( n = 89), especially in those with ILD compared with those without ILD. A third had anti-centromere antibodies and 27.8% had anti-topoisomerase antibodies. Fourteen patients had a disease duration of less than 2 years. ResultsĪmong the 545 SSc patients followed up in our center, 36, including 22 SSc-ILDs, had a PET/CT, whose indication was cancer screening in most cases. The FDG uptake (visual intensity, pattern, SUV max) was systematically recorded in > 30 regions of interest (ROIs) linked to SSc in a blind reviewing by 2 independent nuclear medicine physicians using a standardized form. In our center, SSc patients and controls (non-Hodgkin lymphoma cured after first-line regimen) who had received a PET/CT were screened retrospectively. Progressing ILD could be more metabolically active, suggesting that the 18F-FDG tracer could be a tool in the managing of SSc-ILD. Interstitial lung disease is a common complication of systemic sclerosis (SSc-ILD), and it remains difficult to accurately predict its course.
0 Comments
Read More
Leave a Reply. |